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激动黑质-纹状体通路的多巴胺受体的是()
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激动黑质-纹状体通路的多巴胺受体的是()
A、维生素B
B、卡比多巴
C、金刚烷胺
D、溴隐亭
E、苯海索
时间:2023-02-02 15:54
关键词:
药理学
主管药师
主管药师专业知识
第一章 药理学
答案解析
D
溴隐亭为黑质-纹状体通路的多巴胺受体激动剂,用法应从小剂量开始治疗,缓慢增加剂量,直至获得最大疗效,所以1题答案为D;卡比多巴为脑外脱羧酶抑制剂,不宜进入中枢,仅抑制外周的左旋多巴转化为多巴胺,使循环中左旋多巴含量增高5~10倍,因而它进入中枢的量也增多,所以2题答案为B;金刚烷胺为原始抗病毒药,后发现其也有抗帕金森病的作用,疗效不及左旋多巴,也能致惊厥,故癫痫患者禁用,所以3题答案为C。
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